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   Articles with "hhip" as a keyword



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Single-cell analysis identifies a key role for Hhip in murine coronal suture development

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recommendations! Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-27402-5

Abstract: Craniofacial development depends on formation and maintenance of sutures between bones of the skull. In sutures, growth occurs at osteogenic fronts along the edge of each bone, and suture mesenchyme separates adjacent bones. Here, we… read more here.

Keywords: development; single cell; coronal suture; hhip ... See more keywords
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Hedgehog interacting protein as a circulating biomarker in women with obesity: a cross-sectional study and intervention studies.

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recommendations! Published in 2023 at "Annals of medicine"

DOI: 10.1080/07853890.2023.2206162

Abstract: BACKGROUND Although a study found a significant increase in serum hedgehog interacting protein (HHIP) concentrations in impaired fasting blood glucose, impaired glucose tolerance and newly diagnosed T2DM patients, the variation in circulating HHIP levels in… read more here.

Keywords: hedgehog interacting; interacting protein; hhip; obesity ... See more keywords
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Downregulation of hedgehog-interacting protein (HHIP) contributes to hexavalent chromium-induced malignant transformation of human bronchial epithelial cells.

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recommendations! Published in 2020 at "Carcinogenesis"

DOI: 10.1093/carcin/bgaa085

Abstract: Hexavalent chromium [Cr(VI)] is a potent human lung carcinogen. Multiple mechanisms have been proposed that contribute to Cr(VI)-induced lung carcinogenesis including oxidative stress, DNA damage, genomic instability, and epigenetic modulation. However, the molecular mechanisms and… read more here.

Keywords: transformed cells; hedgehog interacting; hhip; hexavalent chromium ... See more keywords
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Inhibition of HHIP Promoter Methylation Suppresses Human Gastric Cancer Cell Proliferation and Migration

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recommendations! Published in 2018 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000487875

Abstract: Background/Aims: Human hedgehog-interacting protein (HHIP) is a negative regulator of the hedgehog (HH) signaling pathway. It is deregulated in gastric cancer. The underlying molecular mechanism of HHIP-induced inhibition of HH signaling remains to be determined.… read more here.

Keywords: hhip; gastric cancer; proliferation; migration ... See more keywords
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Natural Antisense Long Noncoding RNA HHIP-AS1 Suppresses Non-Small-Cell Lung Cancer Progression by Increasing HHIP Stability via Interaction with CELF2.

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recommendations! Published in 2022 at "Critical reviews in eukaryotic gene expression"

DOI: 10.1615/critreveukaryotgeneexpr.2022043174

Abstract: Non-small-cell lung cancer (NSCLC) is a major category of lung cancer, with high incidence and high mortality. Natural antisense long noncoding RNAs (lncRNAs) are involved in the development of NSCLC via their regulation of biological… read more here.

Keywords: hhip as1; lung cancer; hhip; antisense ... See more keywords