Hydrophobic/Hydrophilic Ratio of Amphiphilic Helix Mimetics Determines the Effects on Islet Amyloid Polypeptide Aggregation
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DOI: 10.1021/acs.jcim.1c01566
Abstract: Amyloid depositions of human islet amyloid polypeptides (hIAPP) are associated with type II diabetes (T2D) impacting millions of people globally. Accordingly, strategies against hIAPP aggregation are essential for the prevention and eventual treatment of the… read more here.
Keywords: aggregation; hydrophobic hydrophilic; helix mimetics; hiapp aggregation ... See more keywords