LAUSR

Iron overload facilitates neonatal hypoxic–ischemic brain damage via SLC7A11‐mediated ferroptosis

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2 Published in 2023 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.25184

Abstract: Oxidative damage and cell death are involved in the pathogenesis of hypoxic–ischemic brain damage (HIBD). Ferroptosis is a newly identified mode of cell death that results from the oxidative damage induced by excessive iron. In… read more here.

Keywords: brain damage; iron; ferroptosis; hibd ... See more keywords

Long non-coding RNA MALAT1 sponges microRNA-429 to regulate apoptosis of hippocampal neurons in hypoxic-ischemic brain damage by regulating WNT1

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0 Published in 2019 at "Brain Research Bulletin"

DOI: 10.1016/j.brainresbull.2019.06.004

Abstract: Hypoxic-ischemic brain damage (HIBD) is a common neurological disorder. Emerging reports reveal that long non-coding RNAs and microRNAs (miRs) are implicated in the progress of HIBD. In this study we tried to ascertain whether lncRNA… read more here.

Keywords: apoptosis; mir 429; hibd; malat1 ... See more keywords

NF-κB signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain damage

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0 Published in 2019 at "Cell Cycle"

DOI: 10.1080/15384101.2019.1608128

Abstract: ABSTRACT NF-κB is a core transcription factor, the activation of which can lead to hypoxic-ischemic brain damage (HIBD), while RCAN1 plays a protective role in HIBD. However, the relationship between NF-κB and RCAN1 in HIBD… read more here.

Keywords: rcan1; hibd; neuronal apoptosis; signaling pathway ... See more keywords