Modulating Nrf2 transcription factor activity: Revealing the regulatory mechanisms of antioxidant defenses during hibernation in 13-lined ground squirrels.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biochemistry and function"
DOI: 10.1002/cbf.3627
Abstract: Mammalian hibernators undergo major behavioural, physiological and biochemical changes to survive hypothermia, ischaemia-reperfusion and finite fuel reserves during days or weeks of continuous torpor. During hibernation, the 13-lined ground squirrel (Ictidomys tridecemlineatus) undergoes a global… read more here.
Keywords: transcription; nrf2 transcription; hibernation lined; antioxidant defenses ... See more keywords
Integrated transcriptomic and metabolomic analysis reveals adaptive changes of hibernating retinas
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26030
Abstract: Hibernation is a seasonally adaptive strategy that allows hibernators to live through extremely cold conditions. Despite the profound reduction of blood flow to the retinas, hibernation causes no lasting retinal injury. Instead, hibernators show an… read more here.
Keywords: transcriptomic metabolomic; analysis; hibernating retinas; hibernation ... See more keywords
Changes in neocortical and hippocampal microglial cells during hibernation
Sign Up to like & getrecommendations! Published in 2017 at "Brain Structure and Function"
DOI: 10.1007/s00429-017-1596-7
Abstract: Mammalian hibernation proceeds alongside a wide range of complex brain adaptive changes that appear to protect the brain from extreme hypoxia and hypothermia. Using immunofluorescence, confocal microscopy, quantitative analysis methods and intracellular injections, we have… read more here.
Keywords: neocortical hippocampal; hibernation; cells hibernation; changes neocortical ... See more keywords
Modifications of the axon initial segment during the hibernation of the Syrian hamster
Sign Up to like & getrecommendations! Published in 2018 at "Brain Structure and Function"
DOI: 10.1007/s00429-018-1753-7
Abstract: Mammalian hibernation is a natural process in which the brain undergoes profound adaptive changes that appear to protect the brain from extreme hypoxia and hypothermia. In addition to a virtual cessation of neural and metabolic… read more here.
Keywords: initial segment; axon initial; hibernation; hibernation syrian ... See more keywords
A Novel AEB-AODV Based AADITHYA Cross Layer Design Hibernation Algorithm for Energy Optimization in WSN
Sign Up to like & getrecommendations! Published in 2021 at "Wireless Personal Communications"
DOI: 10.1007/s11277-020-07929-4
Abstract: Wireless Sensor Networks (WSN) has gained significant importance in current scenario because of its ability to monitor as well as understand the physical environment in terms of different parameters like temperature, humidity, pressure etc. There… read more here.
Keywords: energy; layer; aeb aodv; hibernation ... See more keywords
Identifying and Managing Hibernating Myocardium: What’s New and What Remains Unknown?
Sign Up to like & getrecommendations! Published in 2018 at "Current Heart Failure Reports"
DOI: 10.1007/s11897-018-0396-6
Abstract: Purpose of ReviewHibernation is an important and reversible cause of myocardial dysfunction in ischaemic heart failure.Recent FindingsHibernation is an adaptive process that promotes myocyte survival over maintaining contractile function. It is innate to mammalian physiology,… read more here.
Keywords: hibernation; identifying managing; hibernating myocardium; heart failure ... See more keywords
Chronic total occlusion without collateral blood flow does not exclude myocardial viability and subsequent recovery after revascularization
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nuclear Cardiology"
DOI: 10.1007/s12350-018-1273-0
Abstract: Despite significant progress in drug development improvement, mortality in patients with ischemic heart failure remains high, specifically in medically treated patients. In these patients, the left ventricular ejection fraction (LVEF) is important for long-term outcome;… read more here.
Keywords: improvement; cardiology; viability; myocardium ... See more keywords
Brain inflammatory cytokines and microglia morphology changes throughout hibernation phases in Syrian hamster
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.10.009
Abstract: Hibernators tolerate low metabolism, reduced cerebral blood flow and hypothermia during torpor without noticeable neuronal or synaptic dysfunction upon arousal. Previous studies found extensive changes in brain during torpor, including synaptic rearrangements, documented both morphologically… read more here.
Keywords: cell; arousal; hibernation; inflammatory cytokines ... See more keywords
Skeletal muscle of torpid Richardson's ground squirrels (Urocitellus richardsonii) exhibits a less active form of citrate synthase associated with lowered lysine succinylation.
Sign Up to like & getrecommendations! Published in 2021 at "Cryobiology"
DOI: 10.1016/j.cryobiol.2021.06.006
Abstract: Hibernation is a metabolic/physiological strategy employed by many mammals to cope with periods when energy usage is greater than its input. Animals undergoing hibernation need to greatly reduce their metabolic rate and reshape their catabolic… read more here.
Keywords: citrate synthase; skeletal muscle; muscle; lysine succinylation ... See more keywords
A Unique Energy-Saving Strategy during Hibernation Revealed by Multi-Omics Analysis in the Chinese Alligator
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DOI: 10.1016/j.isci.2020.101202
Abstract: Summary Many ectotherms hibernate in face of the harsh winter conditions to improve their survival rate. However, the molecular mechanism underlying this process remains unclear. Here, we explored the hibernation mechanism of Chinese alligator using… read more here.
Keywords: multi omics; hibernation; unique energy; omics analysis ... See more keywords
Hibernation-like neuroprotection in stroke by attenuating brain metabolic dysfunction
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Neurobiology"
DOI: 10.1016/j.pneurobio.2016.03.002
Abstract: Many mammalian species naturally undergo hibernation, a process that is associated with drastic changes in metabolism and systemic physiology. Their ability to retain an undamaged central nervous system during severely reduced cerebral blood flow has… read more here.
Keywords: hibernation like; neuroprotection stroke; hibernation; stroke attenuating ... See more keywords