Development of an HiBiTâtagged reporter H3N2 influenza A virus and its utility as an antiviral screening platform
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28345
Abstract: The balance of the segmented genome derived from naturally occurring influenza A viruses (IAVs) is delicate and vulnerable to foreign insertions, thus most reporter IAVs up to date are generated using the backbone of the… read more here.
Keywords: platform; hibit tagged; reporter; influenza ... See more keywords
A split NanoLuc complementation-based human norovirus-like particle entry assay facilitates evaluation of anti-norovirus antibodies in live cells.
Sign Up to like & getrecommendations! Published in 2021 at "Antiviral research"
DOI: 10.1016/j.antiviral.2021.105231
Abstract: Human noroviruses (NoVs) are the most common cause of acute gastroenteritis worldwide. One major obstacle in developing NoV vaccines is the lack of robust cell culture for efficacy evaluation. In this study, we successfully developed… read more here.
Keywords: entry; like particle; entry assay; lgbit ... See more keywords
Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies
Sign Up to like & getrecommendations! Published in 2020 at "Cell Chemical Biology"
DOI: 10.1016/j.chembiol.2020.06.006
Abstract: Summary Camelid single-domain antibody fragments (nanobodies) offer the specificity of an antibody in a single 15-kDa immunoglobulin domain. Their small size allows for easy genetic manipulation of the nanobody sequence to incorporate protein tags, facilitating… read more here.
Keywords: monitoring allosteric; hibit; allosteric interactions; interactions cxcr4 ... See more keywords
Tracking of Human Parvovirus B19 Virus-Like Particles Using Short Peptide Tags Reveals a Membrane-Associated Extracellular Release of These Particles
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.01631-22
Abstract: Parvovirus particles are expected to be applied as nanoparticles in drug delivery systems. However, little is known about how nuclear-assembled B19 virus (B19V) virions are released from host cells. ABSTRACT B19 virus (B19V) is a… read more here.
Keywords: parvovirus; b19 virus; hibit; release ... See more keywords