Let-7 miRNAs repress HIC2 to regulate BCL11A transcription and hemoglobin switching.
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood.2023023399
Abstract: The switch from fetal (HBG) to adult (HBB) -globin gene transcription in erythroid cells serves as a paradigm for a complex, clinically relevant developmental gene regulatory program. We previously identified HIC2 as a regulator of… read more here.
Keywords: hic2; adult; hbg; transcription ... See more keywords