β-chlorovinylaldehydes as intermediates in the synthesis of new substituted β–fluoroalkoxyvinyl aldehydes and corresponding alcohols
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2021.109837
Abstract: Abstract A convenient synthesis of a series of new β-fluoroalkoxyvinyl aldehydes and their corresponding alcohols from β-chloro-α,β-unsaturated aldehydes was developed. The etherification reaction and the carbonyl reduction were successfully achieved, affording the desired products in… read more here.
Keywords: corresponding alcohols; chlorovinylaldehydes intermediates; aldehydes corresponding; chloro phenylacrylaldehyde ... See more keywords
Computational Evidence for Tunneling and a Hidden Intermediate in the Biosynthesis of Tetrahydrocannabinol.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c11981
Abstract: Quantum tunneling is computed for a reaction sequence that models the conversion of the ortho-quinone methide of cannabigerolic acid 1 to the decarboxylated product (-)-trans-Δ9-tetrahydrocannabinol (THC, 3). This calculation is the first to evaluate multidimensional… read more here.
Keywords: computational evidence; hidden intermediate; evidence tunneling; reaction ... See more keywords