PO-133 Inhibition of HIF-1α enhances radiation sensitivity in tumour cells and mediates tumour growth decrease in mice
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DOI: 10.1136/esmoopen-2018-eacr25.657
Abstract: Introduction Poor prognosis of many solid tumours is often associated with hypoxic regions and an increased level of hypoxia-inducible-factor-1α (HIF-1α). Previous findings indicate that HIF-1α expression is relevant for radiation resistance. It was shown that… read more here.
Keywords: radiation sensitivity; hif; hif deficient; inhibition ... See more keywords