Construction of a GLUT-1 and HIF-1α gene knockout cell model in HEp-2 cells using the CRISPR/Cas9 technique
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DOI: 10.2147/cmar.s183859
Abstract: Background Glucose transporter (GLUT)-mediated glucose uptake is an important process in the development of laryngeal carcinoma, one of the most common malignancies of the head and neck. GLUT-1, together with HIF-1α, is also an indicator… read more here.
Keywords: hif; gene knockout; hif glut; hep cells ... See more keywords
Oxidative Stress-Induced Sirtuin1 Downregulation Correlates to HIF-1α, GLUT-1, and VEGF-A Upregulation in Th1 Autoimmune Hashimoto’s Thyroiditis
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DOI: 10.3390/ijms22083806
Abstract: In Hashimoto’s thyroiditis (HT), oxidative stress (OS) is driven by Th1 cytokines’ response interfering with the normal function of thyrocytes. OS results from an imbalance between an excessive production of reactive oxygen species (ROS) and… read more here.
Keywords: glut vegf; hashimoto thyroiditis; hif glut; th1 cytokines ... See more keywords