Identification of HIF stabilizer Roxadustat and its possible metabolites in thoroughbred horses for doping control.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3014
Abstract: Hypoxia-inducible factor (HIF) stabilizer belongs to a novel class of pharmacologically active substances, which are capable of inducing the endogenous erythropoietic system. The transcriptional activator HIF has been shown to significantly increase blood haemoglobin, and… read more here.
Keywords: stabilizer roxadustat; phase; hif; hif stabilizer ... See more keywords
HIF Stabilizer Desidustat Protects against Complement-Mediated Diseases
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DOI: 10.1055/a-2347-9919
Abstract: Abstract Complement cascade is a defence mechanism useful for eliminating pathogenic microorganisms and damaged cells. However, activation of alternative complement system can also cause inflammation and promote kidney and retinal disease progression. Inflammation causes tissue… read more here.
Keywords: complement mediated; desidustat; mediated diseases; complement ... See more keywords