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   Articles with "hif vegfa" as a keyword



Cardamonin attenuates cerebral ischemia/reperfusion injury by activating the HIF‐1α/VEGFA pathway

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recommendations! Published in 2022 at "Phytotherapy Research"

DOI: 10.1002/ptr.7409

Abstract: Cardamonin is a chalcone with neuroprotective activity. The aim of our study was to explore the functions and mechanism of action of cardamonin in ischemic stroke. Oxygen–glucose deprivation and reperfusion (OGD/R)‐induced human brain microvascular endothelial… read more here.

Keywords: brain; cardamonin; vegfa pathway; injury ... See more keywords

Swimming exercise reduces H-type vessels by down-regulating the Hif-1α/VEGFa pathway in mice with osteoarthritis of the knee

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recommendations! Published in 2025 at "BMC Musculoskeletal Disorders"

DOI: 10.1186/s12891-025-08903-6

Abstract: The efficacy of swimming in managing knee osteoarthritis (KOA) is well documented. However, the potential of swimming to regulate the Hif-1α/VEGFa pathway and thereby hindering the formation of subchondral bone H-type vessels, remains to be… read more here.

Keywords: bone; vegfa pathway; type vessels; hif vegfa ... See more keywords

MiR-150 regulates human keratinocyte proliferation in hypoxic conditions through targeting HIF-1α and VEGFA: Implications for psoriasis treatment

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0175459

Abstract: Psoriasis is a common and chronic autoimmune skin disease which affects 2 to 3% of the world population. Abnormal proliferation of human keratinocytes is an important feature of psoriasis, along with local hypoxia and vascular… read more here.

Keywords: treatment; hif vegfa; proliferation; mir 150 ... See more keywords

Swimming attenuates tumor growth in CT-26 tumor-bearing mice and suppresses angiogenesis by mediating the HIF-1α/VEGFA pathway

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recommendations! Published in 2022 at "Open Life Sciences"

DOI: 10.1515/biol-2022-0009

Abstract: Abstract Low physical activity correlates with increased cancer risk in various cancer types, including colorectal cancer (CRC). However, the ways in which swimming can benefit CRC remain largely unknown. In this study, mice bearing tumors… read more here.

Keywords: mice; tumor bearing; bearing mice; tumor ... See more keywords

Protective effects of piperine on the retina of mice with streptozotocin-induced diabetes by suppressing HIF-1/VEGFA pathway and promoting PEDF expression.

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recommendations! Published in 2021 at "International journal of ophthalmology"

DOI: 10.18240/ijo.2021.05.04

Abstract: AIM To evaluate the protective mechanisms of piperine in the retina of mice with streptozotocin-induced diabetes. METHODS In experiments in vitro, stimulation by chemical hypoxia was established in ARPE-19 cells. Then, the expression of hypoxia-inducible… read more here.

Keywords: hif vegfa; piperine retina; expression; retina mice ... See more keywords