PERK/eIF2α signaling inhibits HIF-induced gene expression during the unfolded protein response via YB1-dependent regulation of HIF1α translation
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DOI: 10.1093/nar/gky127
Abstract: Abstract HIF1α (hypoxia inducible factor 1α) is the central regulator of the cellular response to low oxygen and its activity is deregulated in multiple human pathologies. Consequently, given the importance of HIF signaling in disease,… read more here.
Keywords: hif1 translation; response; unfolded protein; protein response ... See more keywords