Analysis for higenamine in urine by means of ultra-high-performance liquid chromatography-tandem mass spectrometry: Interpretation of results.
Sign Up to like & getrecommendations! Published in 2018 at "Drug testing and analysis"
DOI: 10.1002/dta.2331
Abstract: Higenamine (Norcoclaurine) is a very popular substance in Chinese medicine and is present in many plants. The substance may be also found in supplements or nutrients, consumption of which may result in violation of anti-doping… read more here.
Keywords: liquid; higenamine; analysis; mass ... See more keywords
The colloidal gold nanoparticle based-lateral flow immunoassay for fast and simple detection of plant-derived doping agent, higenamine.
Sign Up to like & getrecommendations! Published in 2020 at "Drug testing and analysis"
DOI: 10.1002/dta.2981
Abstract: Higenamine (HM), an alkaloid found in various plant species, is obtained when norcoclaurine synthase selectively condenses dopamine and 4-hydroxyphenylacetaldehyde to give (S)-higenamine ((S)-HM). The World Anti-doping Agency has listed HM as a prohibited agent in… read more here.
Keywords: detection; flow immunoassay; plant; higenamine ... See more keywords
Higenamine protects neuronal cells from oxygen‐glucose deprivation/reoxygenation‐induced injury
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DOI: 10.1002/jcb.27656
Abstract: Higenamine, a plant‐based alkaloid, exhibits various properties, such as antiapoptotic and antioxidative effects. Previous studies proved that higenamine possesses potential therapeutic effects for ischemia/reperfusion (I/R) injuries. However, the role of higenamine in cerebral I/R injury… read more here.
Keywords: neuronal cells; higenamine; glucose deprivation; higenamine protects ... See more keywords
Evaluation of Antimycobacterial Activity of Higenamine Using Galleria mellonella as an In Vivo Infection Model
Sign Up to like & getrecommendations! Published in 2018 at "Natural Products and Bioprospecting"
DOI: 10.1007/s13659-018-0152-3
Abstract: The Phytochemical investigation on MeOH extract on the bark of Aristolochia brasiliensis Mart. & Zucc (Aristolochiaceae) led to the isolation of major compound (1) as light brown grainy crystals. The compound was identified as 1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol… read more here.
Keywords: antimycobacterial activity; higenamine; mellonella; model ... See more keywords
Determination of higenamine in dietary supplements by UHPLC/MS/MS method
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.08.017
Abstract: HIGHLIGHTSUPLC/HILIC‐/MS/MS method for higenamine quantification was developed and validated.HILIC mode provide adequate retention of higenamine.Method was applied for higenamine determination in selected dietary supplements. ABSTRACT From 1st January 2017 higenamine was added on the WADA… read more here.
Keywords: uhplc method; dietary supplements; higenamine; determination higenamine ... See more keywords
Identification and characterization of higenamine metabolites in human urine by quadrupole-orbitrap LC-MS/MS for doping control.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2022.114732
Abstract: Higenamine is an alkaloid found in aconite, Annona squamosa, nanzhu (sacred bamboo), and other plants. It can be used to treat coughing, asthma, heart failure, and erectile dysfunction as well as aid in weight loss.… read more here.
Keywords: urine samples; quadrupole orbitrap; characterization higenamine; higenamine ... See more keywords
The stimulant higenamine in weight loss and sports supplements
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DOI: 10.1080/15563650.2018.1497171
Abstract: Abstract Background: Higenamine is a stimulant with cardiovascular properties recently prohibited in sport by the World Anti-Doping Agency (WADA). Higenamine is also a natural constituent of several traditional botanical remedies and is listed as an… read more here.
Keywords: sports supplements; higenamine; loss sports; weight loss ... See more keywords
Higenamine in Plants as a Source of Unintentional Doping
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DOI: 10.3390/plants11030354
Abstract: Background: Higenamine is a β2 agonist of plant origin. The compound has been included in WADA’s prohibited list since 2017. Higenamine may be detected in different plants and many food supplements of natural origin. Methods:… read more here.
Keywords: higenamine containing; higenamine plants; food supplements; medicine ... See more keywords