New Classes of Polycationic Compounds as Preservatives for Ophthalmic Formulations
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2536-9
Abstract: PurposeThe purpose of this research work was to develop new polycationic compounds based on pyridine and piperidine structures with high antimicrobial activities against bacteria and fungi. Furthermore, the compounds should offer a lower toxicity than… read more here.
Keywords: classes polycationic; ophthalmic formulations; high antimicrobial; preservatives ophthalmic ... See more keywords
Copper-containing glass ceramic with high antimicrobial efficacy
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09946-9
Abstract: Hospital acquired infections (HAIs) and the emergence of antibiotic resistant strains are major threats to human health. Copper is well known for its high antimicrobial efficacy, including the ability to kill superbugs and the notorious… read more here.
Keywords: antimicrobial efficacy; high antimicrobial; copper; glass ceramic ... See more keywords
HAM-ART: An optimised culture-free Hi-C metagenomics pipeline for tracking antimicrobial resistance genes in complex microbial communities
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009776
Abstract: Shotgun metagenomics is a powerful tool to identify antimicrobial resistance (AMR) genes in microbiomes but has the limitation that extrachromosomal DNA, such as plasmids, cannot be linked with the host bacterial chromosome. Here we present… read more here.
Keywords: ham art; resistance; pipeline; antimicrobial resistance ... See more keywords