Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.1c01995
Abstract: A series of 5-aryl-2-amino-imidazothiadiazole (ITD) derivatives were identified by a phenotype-based high-throughput screening using a blood stage Plasmodium falciparum (Pf) growth inhibition assay. A lead optimization program focused on improving antiplasmodium potency, selectivity against human… read more here.
Keywords: single dose; pharmacology; blood stage; barrier resistance ... See more keywords
Nanocomposite Coatings Based on Polyvinyl Alcohol and Montmorillonite for High-Barrier Food Packaging
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.790157
Abstract: Materials with high barrier properties against oxygen are required for the packaging of many sensitive foods. Since commodity polymers lack these properties, additional barrier materials are used in plastic-based barrier packaging. These are usually more… read more here.
Keywords: barrier; polyvinyl alcohol; packaging; nanocomposite coatings ... See more keywords
Hydrophobic, Sustainable, High-Barrier Regenerated Cellulose Film via a Simple One-Step Silylation Reaction
Sign Up to like & getrecommendations! Published in 2023 at "Polymers"
DOI: 10.3390/polym15081901
Abstract: With the increasing importance of environmental protection, high-performance biopolymer films have received considerable attention as effective alternatives to petroleum-based polymer films. In this study, we developed hydrophobic regenerated cellulose (RC) films with good barrier properties… read more here.
Keywords: sustainable high; hydrophobic sustainable; reaction; regenerated cellulose ... See more keywords