Articles with "high binding" as a keyword



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Glycan-Controlled Human PD-1 Variants Displaying Broad-Spectrum High Binding to PD-1 Ligands Potentiate T Cell.

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Published in 2023 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.3c00003

Abstract: Although therapeutic immunoglobulin G (IgG) antibodies that regulate the activity of immune checkpoints bring innovation to the field of immuno-oncology, they are still limited in their efficiency to infiltrate the tumor microenvironment due to their… read more here.

Keywords: hpd; high binding; glycan controlled; controlled human ... See more keywords