Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging.
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DOI: 10.1021/acs.jmedchem.1c01706
Abstract: Monoacylglycerol lipase (MAGL) is one of the key enzymes in the endocannabinoid system. Inhibition of MAGL has been proposed as an attractive approach for the treatment of various diseases. In this study, we designed and… read more here.
Keywords: monoacylglycerol lipase; brain; pet; high brain ... See more keywords