Flaxseed-derived peptides ameliorate hepatic cholesterol metabolism in Sprague-Dawley rats fed a high-cholesterol and high-fat diet.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.11888
Abstract: BACKGROUND Plant peptides have been reported to have cholesterol-lowering activities. Previous research has found that ≤1k Da flaxseed peptide (FP5 ) reduces cholesterol absorption and synthesis in vitro. In this research, we investigate the cholesterol-lowering… read more here.
Keywords: high cholesterol; cholesterol; hepatic cholesterol; fed high ... See more keywords
Quercetin administration post-weaning attenuates high-fructose, high-cholesterol diet-induced hepatic steatosis in growing, female, Sprague Dawley rat pups.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.9984
Abstract: BACKGROUND Fructose and cholesterol-rich diets are implicated in the upsurge of metabolic syndrome (MetS). Phytochemicals are being explored as alternatives for the prevention and management of MetS. Thirty-six, 21-day old, female, Sprague Dawley rats fed… read more here.
Keywords: diet induced; group; cholesterol; quercetin ... See more keywords
High Cholesterol at the Heart of Phagolysosomal Damage.
Sign Up to like & getrecommendations! Published in 2018 at "Cell metabolism"
DOI: 10.1016/j.cmet.2018.02.015
Abstract: Phagolysosome membrane rupture can trigger a maladaptive immune response that promotes tissue damage. In Science, Cantuti-Castelvetri et al. (2018) report that cholesterol-rich myelin debris overwhelms reverse cholesterol transport in aged phagocytes, leading to cholesterol crystal formation,… read more here.
Keywords: phagolysosomal damage; cholesterol; damage; heart phagolysosomal ... See more keywords
Screening for lactic acid bacteria in traditional fermented Tibetan yak milk and evaluating their probiotic and cholesterol-lowering potentials in rats fed a high-cholesterol diet
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.03.021
Abstract: Abstract The objectives of the present study were to screen cholesterol-lowering lactic acid bacteria from traditional fermented Tibetan yak milk, and to evaluate their potential use as cholesterol-reducing probiotics in rats. A total of 115… read more here.
Keywords: cholesterol lowering; cholesterol; fed high; rats fed ... See more keywords
High cholesterol-supplemented diet during gestation and lactation alters liver glycosaminoglycans and associated lipoprotein receptors and results in fat accumulation in adulthood.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition research"
DOI: 10.1016/j.nutres.2021.07.002
Abstract: In utero insults to growing fetus impact its health in adulthood. Glycosaminoglycans (GAGs) are involved in lipoprotein metabolism in the liver and vary both quantitively and qualitatively on feeding adult rats a diet rich in… read more here.
Keywords: accumulation; gestation lactation; cholesterol; diet gestation ... See more keywords
Peripheral metabolic effects of ozone exposure in healthy and diabetic rats on normal or high-cholesterol diet.
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2021.115427
Abstract: Epidemiological studies show that individuals with underlying diabetes and diet-associated ailments are more susceptible than healthy individuals to adverse health effects of air pollution. Exposure to air pollutants can induce metabolic stress and increase cardiometabolic… read more here.
Keywords: exposure; cholesterol diet; metabolic effects; high cholesterol ... See more keywords
Neighborhood social cohesion and disease prevention in Asian immigrant populations
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DOI: 10.1016/j.ypmed.2020.106298
Abstract: In the United States (US), chronic disease risk factors are highly prevalent among Asian immigrant communities, who also exhibit low health screening rates. Perceived neighborhood social cohesion (NSC) has been associated with preventive healthcare use… read more here.
Keywords: neighborhood social; social cohesion; cholesterol; disease ... See more keywords
LXR-Mediated Regulation of Marine-Derived Piericidins Aggravates High-Cholesterol Diet-Induced Cholesterol Metabolism Disorder in Mice.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00175
Abstract: Reported as two antirenal cell carcinoma (RCC) drug candidates, marine-derived compounds piericidin A (PA) and glucopiericidin A (GPA) exhibit hepatotoxicity in renal carcinoma xenograft mice. Proteomics and transcriptomics reveal the hepatotoxicity related with cholesterol disposition… read more here.
Keywords: lxr; cholesterol; mice; cholesterol diet ... See more keywords
High-fat and high-cholesterol diet decreases phosphorylated inositol-requiring kinase-1 and inhibits autophagy process in rat liver
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48973-w
Abstract: Precise molecular pathways involved in the progression of non-alcoholic steatohepatitis (NASH) remain to be elucidated. As Mallory–Denk bodies were occasionally observed in the enlarged hepatocytes in NASH model rat (SHRSP5/Dmcr) fed high-fat and high-cholesterol (HFC)… read more here.
Keywords: phosphorylated inositol; kinase; hfc diet; high fat ... See more keywords
Protective effects of thornback ray muscle protein hydrolysate against dyslipidemia, oxidative stress and reduced fertility induced by high cholesterol diet in adult male rats
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DOI: 10.1039/c8ra00657a
Abstract: Enzymatic thornback ray (Raja clavata) muscle hydrolysates have been shown to have antioxidant and antihypertensive activities in vitro. The Neutrase hydrolysate exhibited the highest activities, so it was investigated along with the undigested muscle to… read more here.
Keywords: thornback ray; muscle; hydrolysate; cholesterol diet ... See more keywords
For lifestyle recommendations, better be rich and well educated
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Preventive Cardiology"
DOI: 10.1093/eurjpc/zwad125.095
Abstract: Type of funding sources: None. Management of cardiovascular risk factors (diabetes, hypertension, and high cholesterol levels) should start by implementing a healthy lifestyle. Whereas lifestyle recommendations are provided irrespective of the patient’s socio-economic status has… read more here.
Keywords: hypertension high; lifestyle recommendations; high cholesterol; diabetes hypertension ... See more keywords