High circulating angiopoietin-2 levels exacerbate pulmonary inflammation but not vascular leak or mortality in endotoxin-induced lung injury in mice
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DOI: 10.1136/thoraxjnl-2017-210413
Abstract: Background Elevated plasma levels of angiopoietin-2 (ANGPT2) have been reported in patients with acute lung injury (ALI); however, it remains unclear whether this increase contributes to, or just marks, the underlying vasculopathic inflammation and leak… read more here.
Keywords: endotoxin induced; vascular leak; leak; mice ... See more keywords
High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation
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DOI: 10.1155/2017/1096385
Abstract: Angiopoietin-like 2 (ANGPTL2) is a proinflammatory protein belonging to the angiopoietin-like family. ANGPTL2 is secreted and detected in the systemic circulation. Different observational clinical studies reported that circulating levels of ANGPTL2 increase significantly in various… read more here.
Keywords: levels angptl2; marker; circulating angptl2; high circulating ... See more keywords