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   Articles with "high doses" as a keyword



High doses of vitamin C plus E reduce strength training-induced improvements in areal bone mineral density in elderly men

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recommendations! Published in 2017 at "European Journal of Applied Physiology"

DOI: 10.1007/s00421-017-3588-y

Abstract: PurposeResistance training is beneficial for maintaining bone mass. We aimed to investigate the skeletal effects of high doses of antioxidants [vitamin C + E (α-tocopherol)] supplementation during 12-week supervised strength training in healthy, elderly menMethodsDesign: double-blinded randomized… read more here.

Keywords: strength; bone mineral; high doses; mineral density ... See more keywords

High Doses of Boron Have No Protective Effect Against Nephrolithiasis or Oxidative Stress in a Rat Model

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recommendations! Published in 2018 at "Biological Trace Element Research"

DOI: 10.1007/s12011-018-1294-1

Abstract: Boron plays roles in the metabolism of calcium, vitamin D, steroid hormones, healthy bone development, and maintenance of cell membranes. The biological effects of boron are dose-dependent but follow a U-shaped pattern, rendering it important… read more here.

Keywords: calcium; doses boron; high doses; effect nephrolithiasis ... See more keywords
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Ionizing radiation damage in 65 nm CMOS technology: Influence of geometry, bias and temperature at ultra-high doses

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recommendations! Published in 2021 at "Microelectronics Reliability"

DOI: 10.1016/j.microrel.2020.114016

Abstract: Abstract We studied the radiation response of 3 different 65 CMOS planar technologies at the ultra-high doses expected to be reached in the HL-LHC, the upgraded large hadron collider of CERN. All the processes studied… read more here.

Keywords: temperature; cmos; ultra high; geometry ... See more keywords
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The effect of high doses of ω-3 fatty acid on the structure of the gastrocnemius muscle and on the lipidic profile of Wistar rats submitted to swimming.

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recommendations! Published in 2020 at "Nutrition"

DOI: 10.1016/j.nut.2020.110832

Abstract: OBJECTIVES Evidence suggests that ω-3 fatty acids (FA) may have an anabolic effect on skeletal muscle. However, questions about dosage, frequency, combined protein supplementation, or different physical exercises remain unanswered. The aim of this study… read more here.

Keywords: gastrocnemius muscle; muscle; effect; high doses ... See more keywords

High Doses of Drugs Extensively Metabolized by CYP3A4 Were Needed to Reach Therapeutic Concentrations in Two Patients Taking Inducers.

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recommendations! Published in 2020 at "Revista colombiana de psiquiatria"

DOI: 10.1016/j.rcp.2018.07.002

Abstract: INTRODUCTION In the last 20 years of clinical practice, the senior author has identified these 2 rare cases in which the patients needed extremely high doses of drugs metabolized by CYP3A4 to reach and maintain… read more here.

Keywords: doses drugs; high doses; therapeutic concentrations; day ... See more keywords

Heart Rate Variability modifications induced by high doses of incobotulinumtoxinA and onabotulinumtoxinA in hemiplegic chronic stroke patients: A single blind randomized controlled, crossover pilot study

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recommendations! Published in 2017 at "Toxicon"

DOI: 10.1016/j.toxicon.2017.08.027

Abstract: Background: Botulinum toxin type A is a valid and safe treatment for focal spasticity, with documented effects on both sympathetic and parasympathetic systems. Heart rate variability can provide detailed information about the control of the… read more here.

Keywords: heart rate; heart; high doses; rate variability ... See more keywords

Discrimination of the effects of three cardiac ion channel blockers using ECG biomarkers and arrhythmia incidence in St. Kitts green monkeys (Chlorocebus Sabaeus).

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recommendations! Published in 2019 at "Journal of pharmacological and toxicological methods"

DOI: 10.1016/j.vascn.2019.05.050

Abstract: 24hr recording with RE. We observed expected drug-related changes in QTcF and JTpc intervals in L2 and VM. We did not observe shortening of JTpc relative to QTcF for Verapamil and Mexiletine, but we did… read more here.

Keywords: three cardiac; effects three; channel; model ... See more keywords

High doses of methylprednisolone causes substantial muscle loss with minimal impact on bone mass and architecture in C57BL/6JRj and RjOrl:SWISS mice.

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recommendations! Published in 2025 at "Scientific reports"

DOI: 10.1038/s41598-025-29729-1

Abstract: Glucocorticoids are widely used to treat chronic autoimmune and inflammatory disorders. Unfortunately, glucocorticoid treatment frequently results in severe adverse effects, such as skeletal muscle atrophy and glucocorticoid-induced osteoporosis (GIO). Developing a reliable small animal model… read more here.

Keywords: mice; loss; muscle; high doses ... See more keywords

Assessing soluble and precipitated phosphorus in heavily manured Oxisols

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recommendations! Published in 2025 at "Soil Research"

DOI: 10.1071/sr25108

Abstract: Context Heavily manured soils often exhibit P accumulation to levels that can pose significant environmental risks. Aim. This study aimed to assess the effect of incubating high doses of dairy liquid manure (DLM) for up… read more here.

Keywords: soluble precipitated; precipitated phosphorus; phosphorus heavily; heavily manured ... See more keywords

Safety of high doses of somatostatin analogs in well differentiated NENs in elderly

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recommendations! Published in 2019 at "Annals of Oncology"

DOI: 10.1093/annonc/mdz245.008

Abstract: Abstract Background Neuroendocrine neoplasms (NENs) are a group of heterogeneous neoplasms which can be treated with different therapies: in well differentiated (WD) NENs analogs of somatostatin (SSA) can be used considering their proved antineoplastic and… read more here.

Keywords: age; differentiated nens; well differentiated; high doses ... See more keywords

Failure of neuromuscular blockade despite high doses of rocuronium and atracurium in a patient with colorectal carcinoma

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recommendations! Published in 2024 at "European Journal of Anaesthesiology"

DOI: 10.1097/eja.0000000000002076

Abstract: Resistance to the effects of rocuronium and other neuromuscular blocking agents (NMBA) has been previously reported, including delayed onset of relaxation, rapid recovery and incomplete paralysis under recommended doses. These conditions have been associated with… read more here.

Keywords: despite high; rocuronium atracurium; doses rocuronium; high doses ... See more keywords