High endothelial venules (HEVs) in immunity, inflammation and cancer
Sign Up to like & getrecommendations! Published in 2021 at "Angiogenesis"
DOI: 10.1007/s10456-021-09792-8
Abstract: High endothelial venules (HEVs) are specialized blood vessels mediating lymphocyte trafficking to lymph nodes (LNs) and other secondary lymphoid organs. By supporting high levels of lymphocyte extravasation from the blood, HEVs play an essential role… read more here.
Keywords: inflammation; endothelial venules; venules hevs; blood ... See more keywords
Molecular Signature of Tumor-Associated High Endothelial Venules That Can Predict Breast Cancer Survival
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Immunology Research"
DOI: 10.1158/2326-6066.cir-21-0369
Abstract: The authors identify a molecular signature of breast tumor–associated high endothelial venules, which correlate with presence of tertiary lymphoid structures and survival, suggesting the signature may provide information for treatment selection and determining prognosis. read more here.
Keywords: molecular signature; tumor associated; signature; high endothelial ... See more keywords
Correlation of MECA-79-positive high endothelial venule density with clinical outcomes in upper tract urothelial carcinoma patients treated with radical nephroureterectomy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.6_suppl.417
Abstract: 417Background: High endothelial venules (HEVs) are present in lymph nodes and tertiary lymphoid organs. It has been reported that low HEV density is associated with the poor prognosis of several carcinomas. MECA-79 antibody recognizes L-selectin… read more here.
Keywords: clinical outcomes; upper tract; hev density; density ... See more keywords