Inhibitory effects of high extracellular l-glutamate concentrations on skeletal myogenesis
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DOI: 10.1038/s41598-025-01840-3
Abstract: l-glutamate (Glu) is accumulated abundantly in skeletal muscle cells and plays a central role in energy production, amino acid metabolism, and protein synthesis. If intracellular Glu leaks due to plasma membrane fragility or injury, it… read more here.
Keywords: glu; high extracellular; muscle; effects high ... See more keywords
Exogenous α-synuclein hinders synaptic communication in cultured cortical primary rat neurons
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DOI: 10.1371/journal.pone.0193763
Abstract: Amyloid aggregates of the protein α-synuclein (αS) called Lewy Bodies (LB) and Lewy Neurites (LN) are the pathological hallmark of Parkinson’s disease (PD) and other synucleinopathies. We have previously shown that high extracellular αS concentrations… read more here.
Keywords: high extracellular; exogenous synuclein; extracellular concentrations; synaptic communication ... See more keywords
Extracellular Calcium-Induced Calcium Transient Regulating the Proliferation of Osteoblasts through Glycolysis Metabolism Pathways
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DOI: 10.3390/ijms24054991
Abstract: During bone remodeling, high extracellular calcium levels accumulated around the resorbing bone tissue as soon as the activation of osteoclasts. However, if and how calcium is involved in the regulation of bone remodeling remains unclear.… read more here.
Keywords: calcium; proliferation; high extracellular; calcium transient ... See more keywords