Articles with "high gfpt1" as a keyword



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High GFPT1 expression predicts unfavorable outcomes in patients with resectable pancreatic ductal adenocarcinoma

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Published in 2021 at "World Journal of Surgical Oncology"

DOI: 10.1186/s12957-021-02147-z

Abstract: Background Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) is the first rate-limiting enzyme of the hexosamine biosynthesis pathway (HBP), which plays a pivotal role in the progression of pancreatic ductal adenocarcinoma (PDAC). Therefore, we investigated the prognostic significance… read more here.

Keywords: gfpt1 expression; pdac; patients resectable; expression ... See more keywords