‘Highly‐Informative’ Genetic Markers Can Bias Conclusions: Examples and General Solutions
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DOI: 10.1111/1755-0998.70011
Abstract: High‐grading bias is the overestimation power in a subset of loci caused by model overfitting. Using both empirical and simulated datasets, we show that high‐grading bias can cause severe overestimation of population structure, and thus… read more here.
Keywords: high grading; grading bias; highly informative; fst ... See more keywords