Abstract P2-04-07: Immune profiling of post neoadjuvant high metastatic risk (RCB-II/III) residual disease in patients with early triple negative breast cancers
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DOI: 10.1158/1538-7445.sabcs16-p2-04-07
Abstract: Background: Poor prognosis in TNBC can be predicted in the significant fraction of patients with large volume residual cancer burden (RCB-II/III) after neoadjuvant chemotherapy (NACT). Whilst residual disease has been characterised to identify “driver” mutations… read more here.
Keywords: high metastatic; rcb iii; metastatic risk; disease ... See more keywords
Mammary Tumor Cells with High Metastatic Potential Are Hypersensitive to Macrophage-Derived HGF
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DOI: 10.1158/2326-6066.cir-19-0234
Abstract: Breast cancer cells selected for high metastatic potential have elevated expression of MET and are hyper-responsive to macrophage-derived HGF, which promotes tumor cell extravasation and outgrowth. Blockade of macrophage-mediated HGF/MET signaling could have therapeutic potential… read more here.
Keywords: high metastatic; cancer cells; cancer; metastatic potential ... See more keywords
Commentary: High-metastatic melanoma cells promote the metastatic capability of low-metastatic melanoma cells via exosomal transfer of miR-411-5p
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DOI: 10.3389/fonc.2022.957035
Abstract: COPYRIGHT © 2022 Li, Guo and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided… read more here.
Keywords: cells promote; melanoma cells; high metastatic; metastatic melanoma ... See more keywords
Extracellular Matrix Derived from High Metastatic Human Breast Cancer Triggers Epithelial-Mesenchymal Transition in Epithelial Breast Cancer Cells through αvβ3 Integrin
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DOI: 10.3390/ijms21082995
Abstract: Alterations in the composition and architecture of the extracellular matrix (ECM) can influence cancer growth and dissemination. During epithelial-mesenchymal transition (EMT), epithelial cells assume a mesenchymal cell phenotype, changing their adhesion profiles from cell-cell contacts… read more here.
Keywords: high metastatic; breast; breast cancer; cancer ... See more keywords