High NPM1-mutant allele burden at diagnosis predicts unfavorable outcomes in de novo AML.
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DOI: 10.1182/blood-2018-01-828467
Abstract: Acute myeloid leukemia (AML) with mutated NPM1 is a newly recognized separate entity in the revised 2016 World Health Organization classification and is associated with a favorable prognosis. Although previous studies have evaluated NPM1 in… read more here.
Keywords: high npm1; novo aml; mutant allele; allele burden ... See more keywords