High sucrose low copper diet in pregnant diabetic rats induces transient oxidative stress, hypoxia, and apoptosis in the offspring's liver.
Sign Up to like & getrecommendations! Published in 2018 at "Birth defects research"
DOI: 10.1002/bdr2.1341
Abstract: BACKGROUND Hyperglycemia-related oxidative stress and hypoxia are important mechanisms responsible for diabetes-induced embryopathy and other complications. High sucrose low copper diet (HSD), but not regular diet (RD), induces type 2 diabetes in the inbred Cohen… read more here.
Keywords: apoptosis; high sucrose; stress hypoxia; sucrose low ... See more keywords
Ultrastructural characterization of vitamin D receptors and metabolizing enzymes in the lipid droplets of the fatty liver in rat.
Sign Up to like & getrecommendations! Published in 2020 at "Acta Histochemica"
DOI: 10.1016/j.acthis.2020.151502
Abstract: Abstract Vitamin D is a steroid hormone with numerous actions in the organism. There are strong evidences that relate vitamin D deficiency with liver lipid metabolism disturbances, but the mechanism of this action is still… read more here.
Keywords: rat; microscopy; high sucrose; lipid droplets ... See more keywords
Catecholaminergic stimulation restores high-sucrose diet-induced hippocampal dysfunction
Sign Up to like & getrecommendations! Published in 2021 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2021.105178
Abstract: Increasing evidence suggests that long-term consumption of high-caloric diets increases the risk of developing cognitive dysfunctions. In the present study, we assessed the catecholaminergic activity in the hippocampus as a modulatory mechanism that is altered… read more here.
Keywords: sucrose diet; long term; stimulation restores; high sucrose ... See more keywords
A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesity
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DOI: 10.1038/s41598-021-90817-z
Abstract: While the dire cardiometabolic consequences of the hypercaloric modern ‘Western’ diet are well known, there is not much information on the health impact of a high sucrose diet not inducing weight gain. Here, we tested… read more here.
Keywords: sucrose diet; inflammation; high sucrose; binge high ... See more keywords
Metformin treatment for 8 days impacts multiple intestinal parameters in high-fat high-sucrose fed mice
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-95117-0
Abstract: Although the mechanism of action of the antidiabetic drug metformin is still a matter of discussions, it is well accepted that the gut plays an important role. To gain more insights into the mechanisms occurring… read more here.
Keywords: hfs diet; high sucrose; fat high; high fat ... See more keywords
Impacts of high-sucrose diet on circadian rhythms in the small intestine of rats
Sign Up to like & getrecommendations! Published in 2019 at "Chronobiology International"
DOI: 10.1080/07420528.2019.1592185
Abstract: ABSTRACT Excessive sucrose intake, known as fructose toxicity, leads to fatty liver, hyperlipidemia, and metabolic syndrome. Circadian disorders also contribute to metabolic syndrome. Here, we investigated the effect of excessive sucrose intake on circadian rhythms… read more here.
Keywords: sucrose diet; rhythms small; circadian rhythms; high sucrose ... See more keywords
Interactive effects of chronic stress and a high-sucrose diet on nonalcoholic fatty liver in young adult male rats
Sign Up to like & getrecommendations! Published in 2017 at "Stress"
DOI: 10.1080/10253890.2017.1381840
Abstract: Abstract Glucocorticoids have been implicated in nonalcoholic fatty liver diseases (NAFLD). The influence of a palatable diet on the response to stress is controversial. This study explored whether a high-sucrose diet could protect from hepatic… read more here.
Keywords: sucrose diet; high sucrose; stress; restraint stress ... See more keywords
Increased total DNA damage and oxidative stress in brain are associated with decreased longevity in high sucrose diet fed WNIN/Gr-Ob obese rats
Sign Up to like & getrecommendations! Published in 2018 at "Nutritional Neuroscience"
DOI: 10.1080/1028415x.2017.1332509
Abstract: Background: Obesity and Type 2 Diabetes (T2D) are chronic nutrient-related disorders that occur together and pose a grave burden to society. They are among the most common causes of ageing and death. Obesity and T2D… read more here.
Keywords: high sucrose; dna damage; stress; oxidative stress ... See more keywords
Effects of acute exposure to a high-fat, high-sucrose diet on gestational glucose tolerance and subsequent maternal health in mice†
Sign Up to like & getrecommendations! Published in 2017 at "Biology of Reproduction"
DOI: 10.1095/biolreprod.116.144543
Abstract: Abstract Gestational diabetesmellitus (GDM) is a common obstetric complication. Half of women who have GDM will go on to develop type 2 diabetes. Understanding the mechanisms by which this occurs requires an animal model of… read more here.
Keywords: pregnancy; hfhs; high sucrose; fat high ... See more keywords
A comparison of the effects of Stevia extract and metformin on metabolic syndrome indices in rats fed with a high-fat, high-sucrose diet.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13242
Abstract: The beneficial effects of Stevia on metabolic indices have been studied in recent years. However, controversial results emphasize the need for further investigation. We aimed to examine and compare the effects of Stevia's hydroalcoholic extract… read more here.
Keywords: stevia extract; sucrose diet; effects stevia; high sucrose ... See more keywords
YAP Targets the TGFβ Pathway to Mediate High-Fat/High-Sucrose Diet-Induced Arterial Stiffness.
Sign Up to like & getrecommendations! Published in 2022 at "Circulation research"
DOI: 10.1161/circresaha.121.320464
Abstract: BACKGROUND Metabolic syndrome is related to cardiovascular diseases, which is attributed in part, to arterial stiffness; however, the mechanisms remain unclear. The present study aimed to investigate the molecular mechanisms of metabolic syndrome-induced arterial stiffness… read more here.
Keywords: high sucrose; sucrose diet; stiffness; high fat ... See more keywords