Articles with "higher mutation" as a keyword



Metastatic adrenocortical carcinoma displays higher mutation rate and tumor heterogeneity than primary tumors

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-06366-z

Abstract: Adrenocortical cancer (ACC) is a rare cancer with poor prognosis and high mortality due to metastatic disease. All reported genetic alterations have been in primary ACC, and it is unknown if there is molecular heterogeneity… read more here.

Keywords: heterogeneity; mutation rate; higher mutation; tumor heterogeneity ... See more keywords