Articles with "highfold design" as a keyword



CycleDesigner: Leveraging CycRFdiffusion and HighFold to Design Cyclic Peptide Binders for Specific Targets

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Published in 2025 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.5c00227

Abstract: Cyclic peptides are potentially therapeutic in clinical applications, due to their great stability and activity. Yet, designing and identifying potential cyclic peptide binders targeting specific targets remains a formidable challenge, entailing significant time and resources.… read more here.

Keywords: specific targets; peptide binders; highfold design; peptide ... See more keywords