Preprint Highlight: ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA- dependent STING signaling.
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DOI: 10.1091/mbc.p22-02-1003
Abstract: Loss-of-function mutations in VPS13C cause familial Parkinson’s disease (PD) and increase the risk to develop the sporadic form of the disease. However, the underlying disease mechanisms remain unclear. It has been previously established that VPS13C… read more here.
Keywords: transfer protein; highlight lysosome; lysosome lipid; vps13c ... See more keywords