A transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aax0396
Abstract: Comparative transcriptomics of olfactory mucosae offers clues into the putative functions of highly abundant ORs in mammals. The mammalian olfactory system displays species-specific adaptations to different ecological niches. To investigate the evolutionary dynamics of olfactory… read more here.
Keywords: osn subtypes; highly abundant; olfactory mucosae; mammalian olfactory ... See more keywords
Abstract 200: Targeting the Highly Abundant Circular RNA, circHeart, in Cardiomyocytes Attenuates Pressure Overload Induced Hypertrophy
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.200
Abstract: Objectives: Circular RNAs (circRNAs) are single-stranded non-coding RNAs that form a covalent closed looped structure and are generated during gene transcription. In our genome-wide analysis of cardiac circRNA expression in both human and mouse hearts… read more here.
Keywords: cardiac hypertrophy; vivo; highly abundant; hypertrophy ... See more keywords
Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-019-0735-1
Abstract: Astrogliosis and activation of microglia are hallmarks of prion diseases in humans and animals. Both were viewed to be rather independent events in disease pathophysiology, with proinflammatory microglia considered to be the potential neurotoxic species… read more here.
Keywords: astrocytes highly; highly abundant; prion; abundant prion ... See more keywords
The Satellite DNAs Populating the Genome of Trigona hyalinata and the Sharing of a Highly Abundant satDNA in Trigona Genus
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14020418
Abstract: Among Meliponini species, c-heterochromatin can occupy large portions of chromosomes. This characteristic could be useful for understanding evolutionary patterns of satellite DNAs (satDNAs), although few sequences have been characterized in these bees. In Trigona, phylogenetically… read more here.
Keywords: satellite dnas; highly abundant; trigona hyalinata; genus ... See more keywords