Abstract A18: microRNA-206 as a potential therapeutic approach for highly-associated NAFLD and HCC
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DOI: 10.1158/1538-7445.transcontrol16-a18
Abstract: Background and Significance: Non-alcoholic fatty liver disease (NAFLD) is a major risk factor for the development of hepatocellular carcinoma (HCC). Even with successful surgical removal, the presence of NAFLD is associated with an increased recurrence… read more here.
Keywords: highly associated; hcc mice; hcc; mir 206 ... See more keywords
Cuplike nuclear morphology is highly associated with IKZF1 deletion in pediatric precursor B-cell ALL.
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DOI: 10.1182/blood.2019000604
Abstract: TO THE EDITOR: Cuplike nuclei (CLN) (nuclei with prominent invagination) are recognized as a distinctive morphologic finding in the blasts of acute myeloid leukemia (AML).[1][1][⇓][2][⇓][3][⇓][4][⇓][5]-[6][6] They are seen in ∼20% of all AML cases[2][2],[4][4],[5][5] and… read more here.
Keywords: highly associated; associated ikzf1; cuplike nuclear; ikzf1 deletion ... See more keywords
Hyperinsulinemia is Highly Associated with Markers of Hepatocytic Senescence in Two Independent Cohorts.
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DOI: 10.2337/db21-1076
Abstract: Cellular senescence is an essentially irreversible growth arrest that occurs in response to various cellular stressors and may contribute to development of type 2 diabetes and Non-Alcoholic Fatty Liver Disease (NAFLD). Here, we investigated whether… read more here.
Keywords: highly associated; hyperinsulinemia highly; liver; senescence ... See more keywords
Genes Possessing the Most Frequent DNA DSBs Are Highly Associated with Development and Cancers, and Essentially Overlap with the rDNA-Contacting Genes
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DOI: 10.3390/ijms23137201
Abstract: Double-strand DNA breakes (DSBs) are the most deleterious and widespread examples of DNA damage. They inevitably originate from endogenous mechanisms in the course of transcription, replication, and recombination, as well as from different exogenous factors.… read more here.
Keywords: highly associated; dna; rdna contacting; dsbs ... See more keywords