Highly Immunogenic DQB1 Mismatch Eplets Are Associated With Development of Chronic Active Antibody-Mediated Rejection: A First Report From Japan.
Sign Up to like & getrecommendations! Published in 2017 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2016.10.022
Abstract: BACKGROUND De novo donor-specific antibody (dnDSA), especially against class II HLA, correlates with chronic active antibody-mediated rejection (CAAMR), which eventually leads to graft loss. It would be helpful if we could identify the patients at… read more here.
Keywords: control; highly immunogenic; antibody; caamr control ... See more keywords
Multicomponent gold nano-glycoconjugate as a highly immunogenic and protective platform against Burkholderia mallei
Sign Up to like & getrecommendations! Published in 2020 at "NPJ Vaccines"
DOI: 10.1038/s41541-020-00229-9
Abstract: Burkholderia mallei (Bm) is a facultative intracellular pathogen and the etiological agent of glanders, a highly infectious zoonotic disease occurring in equines and humans. The intrinsic resistance to antibiotics, lack of specific therapy, high mortality,… read more here.
Keywords: burkholderia mallei; highly immunogenic; antigen; vaccine ... See more keywords
A tumor metastasis‐associated molecule TWIST1 is a favorable target for cancer immunotherapy due to its immunogenicity
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15429
Abstract: Although neoantigens are one of the most favorable targets in cancer immunotherapy, it is less versatile and costly to apply neoantigen‐derived cancer vaccines to patients due to individual variation. It is, therefore, important to find… read more here.
Keywords: highly immunogenic; twist1; tumor; cancer ... See more keywords
Abstract 5625: Targeting the nonsense mediated mRNA decay pathway to prevent the degradation of highly immunogenic frameshift mutated transcripts
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-5625
Abstract: Introduction: Frameshift insertions/deletions (fs-indels) can lead to the generation of immunogenic non-self-peptides which contribute to anti-tumor immune responses. However, fs-indels often generate premature termination codons (PTCs), leading to mRNA degradation by the nonsense mediated mRNA… read more here.
Keywords: cancer; highly immunogenic; degradation; nonsense mediated ... See more keywords
An Attenuated and Highly Immunogenic Variant of the Vaccinia Virus
Sign Up to like & getrecommendations! Published in 2024 at "Acta Naturae"
DOI: 10.32607/actanaturae.27384
Abstract: The vaccinia virus (VACV) has been used for prophylactic immunization against smallpox for many decades. However, the VACV-based vaccine had been highly reactogenic. Therefore, after the eradication of smallpox, the World Health Organization in 1980… read more here.
Keywords: highly immunogenic; virus; vaccinia virus; strain ... See more keywords
SM-COLSARSPROT: Highly Immunogenic Supramutational Synthetic Peptides Covering the World’s Population
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.859905
Abstract: Fifty ~20–amino acid (aa)–long peptides were selected from functionally relevant SARS-CoV-2 S, M, and E proteins for trial B-21 and another 53 common ones, plus some new ones derived from the virus’ main genetic variants… read more here.
Keywords: colsarsprot highly; highly immunogenic; immunogenic supramutational; world ... See more keywords