The genome of the Cauliflower mosaic virus, a plant pararetrovirus, is highly methylated in the nucleus
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DOI: 10.1002/1873-3468.13852
Abstract: Cytosine methylation is an important defense against invasive DNAs. Here, cytosine methylation profiles of a plant pararetrovirus, Cauliflower mosaic virus (CaMV), were investigated. Nuclear CaMV DNA is highly methylated throughout the genome including at transcription… read more here.
Keywords: methylation; highly methylated; mosaic virus; cauliflower mosaic ... See more keywords
Total Synthesis of the Highly N-Methylated Acetylene-Containing Anticancer Peptide Jahanyne.
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DOI: 10.1021/acs.orglett.7b03925
Abstract: The first total synthesis of the highly N-methylated acetylene-containing lipopeptide jahanyne, an apoptosis-inducing natural product from marine cyanobacteria, is reported. A late-stage solution-phase coupling enabled introduction of the C-terminal ketone pyrrolidine moiety. A modified Fmoc… read more here.
Keywords: jahanyne; highly methylated; methylated acetylene; total synthesis ... See more keywords
Preparation of N-alkylamides of highly methylated (HM) citrus pectin
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DOI: 10.17221/3494-cjfs
Abstract: N-Alkylamides of highly methylated (HM) citrus pectin (DM = 73%) were prepared using heterogeneous amino-dealkoxylation (aminolysis) with five selected n-alkylamines. The reaction was carried out in N,N-dimethylformamide at 8°C (n-butylamine), 25°C (n-hexylamine), and 45°C (n-octylamine,… read more here.
Keywords: highly methylated; methylated citrus; citrus pectin; pectin ... See more keywords
Total Synthesis of the Highly N-Methylated Peptides Carmabin A and Dragomabin
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DOI: 10.3390/md16090338
Abstract: The first total synthesis of carmabin A and dragomabin was achieved at 52.3 mg and 43.8 mg scale, respectively. The synthesis led to determination of the configuration of carmabin A and reassignment of the configuration… read more here.
Keywords: highly methylated; carmabin dragomabin; total synthesis; methylated peptides ... See more keywords