Highly regio- and stereoselective palladium-catalyzed allene bifunctionalization cascade via π-allyl intermediate
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.08.021
Abstract: Abstract We report a palladium-catalyzed allene bifunctionalization reaction that forms C C and either C O or C N bonds in one pot with excellent regio- and stereoselectivity. Carboxylic acids, amides, and hydroxide are all… read more here.
Keywords: allene bifunctionalization; palladium catalyzed; highly regio; catalyzed allene ... See more keywords
Highly Regio- and Stereoselective Intramolecular Rearrangement of Glycidol Acetal to Alkoxy Cyclic Acetals.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02397
Abstract: A new class of highly regio- and stereoselective intramolecular rearrangements of glycidol acetals to produce alkoxylated 1,3-dioxolane/1,3-dioxane is demonstrated. Selective Lewis acid activation of acetal generates an oxocarbenium ion that initiates the epoxide ring-opening event,… read more here.
Keywords: intramolecular rearrangement; rearrangement glycidol; glycidol acetal; regio stereoselective ... See more keywords
Rhodium-Catalyzed Highly Regio- and Enantioselective Reductive Cyclization of Alkyne-Tethered Cyclohexadienones
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.7b04054
Abstract: Rhodium-catalyzed asymmetric hydrogenation of alkyne-tethered cyclohexadienones enables highly regio- and enantioselective reductive cyclization to afford cis-hydrobenzofurans and cis-hydroindoles in high yields. Desymmetrization of 1,3-diyne-tethered cyclohexadienones was also explored, wherein the intramolecular coordination of a Rh… read more here.
Keywords: rhodium catalyzed; reductive cyclization; alkyne tethered; highly regio ... See more keywords
Highly Regio- and Enantioselective Reductive Coupling of Alkynes and Aldehydes via Photoredox Cobalt Dual Catalysis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c03527
Abstract: A Co-catalyzed highly regio- and enantioselective reductive coupling of alkynes and aldehydes has been developed under visible light photoredox dual catalysis. A variety of enantioenriched allylic alcohols have been obtained by using unsymmetrical internal alkynes… read more here.
Keywords: regio enantioselective; enantioselective reductive; alkynes aldehydes; reductive coupling ... See more keywords
Challenging Task of Ni-Catalyzed Highly Regio-/Enantioselective Semihydrogenation of Racemic Tetrasubstituted Allenes via a Kinetic Resolution Process.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c12597
Abstract: The first earth-abundant transition metal Ni-catalyzed highly regio- and enantioselective semihydrogenation of racemic tetrasubstituted allenes via a kinetic resolution process as a challenging task was well established. This protocol furnishes expedient access to a diversity… read more here.
Keywords: regio enantioselective; semihydrogenation; catalyzed highly; highly regio ... See more keywords
Highly Regio- and Stereoselective Catalytic Synthesis of Conjugated Dienes and Polyenes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.8b05421
Abstract: Conjugated dienes and polyenes are typically synthesized by sequential introduction of C═C bonds. Here, we report a practical and scalable, catalytic dienylation that is highly regio- and stereoselective for both C═C bonds. The reaction is… read more here.
Keywords: conjugated dienes; dienes polyenes; stereoselective catalytic; regio stereoselective ... See more keywords
Chiral cis-iron(ii) complexes with metal- and ligand-centered chirality for highly regio- and enantioselective alkylation of N-heteroaromatics†
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c9sc04858h
Abstract: Iron-catalyzed highly regio- and enantioselective organic transformations with generality and broad substrate scope have profound applications in modern synthetic chemistry; an example is herein described based on cis-FeII complexes having metal- and ligand-centered chirality. The… read more here.
Keywords: cis; regio enantioselective; metal; highly regio ... See more keywords
Highly regio- and diastereoselective (3+3)-cycloannulation of carbonyl ylides and 2-(1-alkynyl)-2-alken-1-ones enabled by silver catalysis.
Sign Up to like & getrecommendations! Published in 2025 at "Chemical communications"
DOI: 10.1039/d5cc02003d
Abstract: A highly regio- and diastereoselective (3+3)-cycloannulation of in situ generated carbonyl ylides and 2-(1-alkynyl)-2-alken-1-ones enabled by silver catalysis is reported. This work is the first to describe a silver catalysed synthesis of 3,4-fused furan with… read more here.
Keywords: ylides alkynyl; diastereoselective cycloannulation; carbonyl ylides; regio diastereoselective ... See more keywords