A four-drug standardized short regimen for highly resistant TB in South-West Nigeria.
Sign Up to like & getrecommendations! Published in 2023 at "International health"
DOI: 10.1093/inthealth/ihad023
Abstract: BACKGROUND Patients with TB resistant to rifampicin (Rr-TB), and those with additional resistance to fluoroquinolones (pre-XDR-TB), should be treated with bedaquiline-pretomanid-linezolid-moxifloxacin and bedaquiline-pretomanid-linezolid, respectively. However, pretomanid is not yet widely available. METHODS This is a… read more here.
Keywords: drug standardized; bedaquiline; pre xdr; highly resistant ... See more keywords
Resistance to Fipronil in the Common Bed Bug (Hemiptera: Cimicidae)
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Entomology"
DOI: 10.1093/jme/tjab040
Abstract: Abstract Cimex lectularius L. populations have been documented worldwide to be resistant to pyrethroids and neonicotinoids, insecticides that have been widely used to control bed bugs. There is an urgent need to discover new active… read more here.
Keywords: highly resistant; resistance fipronil; bed bug; resistance ... See more keywords
Restoration of pyrethroid susceptibility in a highly resistant Aedes aegypti population
Sign Up to like & getrecommendations! Published in 2018 at "Biology Letters"
DOI: 10.1098/rsbl.2018.0022
Abstract: Insecticide resistance has evolved in disease vectors worldwide, creating the urgent need to either develop new control methods or restore insecticide susceptibility to regain use of existing tools. Here we show that phenotypic susceptibility can… read more here.
Keywords: aedes aegypti; susceptibility; highly resistant; pyrethroid susceptibility ... See more keywords
Identification of Putative Drug Targets in Highly Resistant Gram-Negative Bacteria; and Drug Discovery Against Glycyl-tRNA Synthetase as a New Target
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics and Biology Insights"
DOI: 10.1177/11779322231152980
Abstract: Background: Gram-negative bacterial infections are on the rise due to the high prevalence of multidrug-resistant bacteria, and efforts must be made to identify novel drug targets and then new antibiotics. Methods: In the upstream part,… read more here.
Keywords: resistant gram; highly resistant; drug; drug targets ... See more keywords
High prevalence of antimicrobial resistance and multidrug resistance among bacterial isolates from diseased pets: Retrospective laboratory data (2015–2017)
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0277664
Abstract: Laboratory surveillance and the monitoring of antimicrobial resistance (AMR) trends and patterns among local isolates have been highly effective in providing comprehensive information for public health decision-making. A total of 396 cases along with 449… read more here.
Keywords: laboratory; 2015 2017; resistance; isolates highly ... See more keywords
Diagnostic Evasion of Highly-Resistant Microorganisms: A Critical Factor in Nosocomial Outbreaks
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.02128
Abstract: Highly resistant microorganisms (HRMOs) may evade screening strategies used in routine diagnostics. Bacteria that have evolved to evade diagnostic tests may have a selective advantage in the nosocomial environment. Evasion of resistance detection can result… read more here.
Keywords: evasion; diagnostic evasion; highly resistant; resistance ... See more keywords
The Role of nmcR, ampR, and ampD in the Regulation of the Class A Carbapenemase NmcA in Enterobacter ludwigii
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.794134
Abstract: Various carbapenemases have been identified in the Enterobacteriaceae. However, the induction and corresponding regulator genes of carbapenemase NmcA has rarely been detected in the Enterobacter cloacae complex (ECC). The NmcA-positive isolate ECC NR1491 was first… read more here.
Keywords: role nmcr; nmcr ampr; carbapenemase nmca; highly resistant ... See more keywords
Transgenic Rice Plants Expressing Artificial miRNA Targeting the Rice Stripe Virus MP Gene Are Highly Resistant to the Virus
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11020332
Abstract: Simple Summary Rice stripe virus is a disastrous viral disease that causes significant yield losses in rice production in South, Southeast, and East Asian countries. To decrease the use of chemical insecticides, genetic engineering has… read more here.
Keywords: rice stripe; stripe virus; rice; highly resistant ... See more keywords
Comparative Metabolomic Profiling of Horse Gram (Macrotyloma uniflorum (Lam.) Verdc.) Genotypes for Horse Gram Yellow Mosaic Virus Resistance
Sign Up to like & getrecommendations! Published in 2023 at "Metabolites"
DOI: 10.3390/metabo13020165
Abstract: Horse gram (Macrotyloma uniflorum (Lam.) Verdc.) is an under-utilized legume grown in India. It is a good source of protein, carbohydrates, dietary fiber, minerals, and vitamins. We screened 252 horse gram germplasm accessions for horse… read more here.
Keywords: horse; gram macrotyloma; horse gram; resistance ... See more keywords