Enzymatic removal of sialic acid enables iCIEF stability monitoring of charge variants of a highly sialylated bispecific antibody
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DOI: 10.1002/elps.202100259
Abstract: Antibody‐based therapeutic proteins have highly complex molecular structures. The final therapeutic protein product may contain a wide range of charge variants. Accurate analysis of this charge variant composition is critical to determine manufacturing process consistency… read more here.
Keywords: highly sialylated; charge variants; sialylated bispecific; stability ... See more keywords