Class-Switch Recombination (CSR)/Hyper-IgM (HIGM) Syndromes and Phosphoinositide 3-Kinase (PI3K) Defects
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DOI: 10.3389/fimmu.2018.02172
Abstract: Antibody production and function represent an essential part of the immune response, particularly in fighting bacterial and viral infections. Multiple immunological phenotypes can result in dysregulation of the immune system humoral compartment, including class-switch recombination… read more here.
Keywords: higm syndromes; class switch; igm; switch recombination ... See more keywords