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Human IL-17 and TNF-α Additively or Synergistically Regulate the Expression of Proinflammatory Genes, Coagulation-Related Genes, and Tight Junction Genes in Porcine Aortic Endothelial Cells

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.857311

Abstract: Immune rejection is the major limitation for porcine xenograft survival in primate recipients. Proinflammatory cytokines play important roles in immune rejection and have been found to mediate the pathological effects in various clinical and experimental… read more here.

Keywords: coagulation; additively synergistically; expression; human tnf ... See more keywords