Articles with "hilic method" as a keyword



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A HILIC-MS/MS method development and validation for the quantitation of 13 acylcarnitines in human serum

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Published in 2022 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-022-03940-9

Abstract: Acylcarnitines are essential diagnostic markers for complex diseases and fatty acid metabolism disorders, and play an important role in cardiovascular diseases. Herein, a HILIC-MS/MS method was developed and validated for the rapid quantitation of the… read more here.

Keywords: method; quantitation acylcarnitines; quantitation; c18 ... See more keywords
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An Experimental Design Approach to Quantitative Expression for Quality Control of a Multicomponent Antidiabetic Formulation by the HILIC Method

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27103135

Abstract: A rapid and reproducible hydrophilic liquid chromatography (HILIC) process was established for concomitant determination of remogliflozin etabonate (RE), vildagliptin (VD), and metformin (MF) in a formulation. A face-centered central composite experimental design was employed to… read more here.

Keywords: quality; experimental design; hilic method; formulation ... See more keywords