The Influence of Hindlimb Unloading on Bone and Muscle Tissues in Rat Model
Sign Up to like & getrecommendations! Published in 2017 at "BioNanoScience"
DOI: 10.1007/s12668-016-0288-8
Abstract: Numerous results indicate on interactions between muscles and bones. Thus, mechanical, genetic, endocrine, and age-related factors influence both tissues at the same time. Nevertheless, the details of physiological mechanisms of interaction between muscles and bones… read more here.
Keywords: muscles bones; hindlimb unloading; muscle; bone ... See more keywords
Repetitive transcranial magnetic stimulation ameliorates recognition memory impairment induced by hindlimb unloading in mice associated with BDNF/TrkB signaling
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Research"
DOI: 10.1016/j.neures.2019.04.002
Abstract: Repetitive transcranial magnetic stimulation (rTMS), which could improve learning and memory, is widely used in psychiatry and neurology as a therapeutic approach. There are few studies reporting effective countermeasures to cognition decline in astronauts during… read more here.
Keywords: hindlimb unloading; repetitive transcranial; rtms; transcranial magnetic ... See more keywords
Insulin and exercise improved muscle function in rats with severe burns and hindlimb unloading
Sign Up to like & getrecommendations! Published in 2019 at "Physiological Reports"
DOI: 10.14814/phy2.14158
Abstract: Prior work established that exercise alleviates muscle function loss in a clinically relevant rodent model mimicking the clinical sequelae of severely burned patients. On the basis of these data, we posit that pharmacologic treatment with… read more here.
Keywords: insulin; hindlimb unloading; muscle; muscle function ... See more keywords
The Skeletal Cellular and Molecular Underpinning of the Murine Hindlimb Unloading Model
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.749464
Abstract: Bone adaptation to spaceflight results in bone loss at weight bearing sites following the absence of the stimulus represented by ground force. The rodent hindlimb unloading model was designed to mimic the loss of mechanical… read more here.
Keywords: loss; cellular molecular; unloading model; hindlimb unloading ... See more keywords
Effect of Microgravity on the Gut Microbiota Bacterial Composition in a Hindlimb Unloading Model
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12111865
Abstract: We utilised a ground-based microgravity hindlimb unloading (HU) mouse model to elucidate the gut microbiota bacterial changes in mice under a simulated microgravity environment. Four-month-old, male C57/Bl6 mice were randomly divided into ground-based controls and… read more here.
Keywords: microgravity; gut microbiota; microbiota bacterial; mice ... See more keywords