Hinokitiol ablates myofibroblast activation in precancerous oral submucous fibrosis by targeting Snail
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Toxicology"
DOI: 10.1002/tox.22531
Abstract: Oral submucous fibrosis (OSF) is a precancerous condition with symptoms of limited mouth opening and areca nut chewing habit has been implicated in its pathogenesis. Hinokitiol, a natural tropolone derived from Chamacyparis taiwanensis, has been… read more here.
Keywords: hinokitiol ablates; submucous fibrosis; hinokitiol; snail ... See more keywords
New therapeutic strategy of hinokitiol in haemorrhagic shock‐induced liver injury
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14070
Abstract: Haemorrhagic shock and resuscitation (HS/R) may cause global ischaemia‐reperfusion injury, which can result in systemic inflammation, multiorgan failure (particularly liver failure) and high mortality. Hinokitiol, a bioactive tropolone‐related compound, exhibits antiplatelet and anti‐inflammatory activities. Targeting… read more here.
Keywords: hinokitiol; activation; liver injury; injury ... See more keywords
Hinokitiol inhibits Aspergillus fumigatus by interfering with the cell membrane and cell wall
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1132042
Abstract: Hinokitiol (β-thujaplicin) is an important component of the essential oil extracted from Chamaecyparis obtuse, which prevents the decay and decomposition of temple and shrine buildings in Japan. Hinokiol has been shown to have a detrimental… read more here.
Keywords: cell membrane; cell; cell wall; hinokitiol ... See more keywords
Hinokitiol Inhibits Migration of A549 Lung Cancer Cells via Suppression of MMPs and Induction of Antioxidant Enzymes and Apoptosis
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19040939
Abstract: Hinokitiol, a natural monoterpenoid from the heartwood of Calocedrus formosana, has been reported to have anticancer effects against various cancer cell lines. However, the detailed molecular mechanisms and the inhibiting roles of hinokitiol on adenocarcinoma… read more here.
Keywords: a549 cells; migration; hinokitiol; lung cancer ... See more keywords
Calcium Phosphate Cement with Antimicrobial Properties and Radiopacity as an Endodontic Material
Sign Up to like & getrecommendations! Published in 2017 at "Materials"
DOI: 10.3390/ma10111256
Abstract: Calcium phosphate cements (CPCs) have several advantages for use as endodontic materials, and such advantages include ease of use, biocompatibility, potential hydroxyapatite-forming ability, and bond creation between the dentin and appropriate filling materials. However, unlike… read more here.
Keywords: calcium phosphate; antibacterial properties; cpc; hinokitiol ... See more keywords
Hinokitiol impedes tumor drug resistance by suppressing protein kinase B/mammalian targets of rapamycin axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer"
DOI: 10.7150/jca.69449
Abstract: Chemotherapy is a treatment method commonly used for cancer and that patients showing low to no response to the treatment often developed drug resistance via multiple mechanisms. Natural products have been shown to reduce tumor… read more here.
Keywords: kinase; resistance; drug resistance; tumor drug ... See more keywords