HINT1 deficiency in aged mice reduces anxiety-like and depression-like behaviours and enhances cognitive performances
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DOI: 10.1016/j.exger.2021.111683
Abstract: Histidine triad nucleotide-binding protein 1 (HINT1) is regarded as a haplo-insufficient tumour suppressor and is closely associated with many neuropsychiatric disorders, including major depressive disorders. In addition, HINT1 knockout (KO) mice exhibit anxiolytic-like behaviour, antidepression-like… read more here.
Keywords: hint1 mice; like depression; mice; depression like ... See more keywords