Natural bioactive 4-Hydroxyisophthalic acid (4-HIPA) exhibited antiproliferative potential by upregulating apoptotic markers in in vitro and in vivo cancer models
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology Reports"
DOI: 10.1007/s11033-020-05617-x
Abstract: There is tremendous scope for identifying novel anti-cancer molecules from the unexplored reserves of plant kingdom. The application of dietary supplementation or medicine derived from such sources is a promising approach towards treatment of cancer.… read more here.
Keywords: antiproliferative potential; acid hipa; hipa; hydroxyisophthalic acid ... See more keywords
The kinases HipA and HipA7 phosphorylate different substrate pools in Escherichia coli to promote multidrug tolerance
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DOI: 10.1126/scisignal.aat5750
Abstract: Differences in the targets of HipA and its variant HipA7 may explain why these kinases have different effects on bacterial persistence. Balancing bacterial growth with drug resistance Within some bacterial populations, a subset of cells… read more here.
Keywords: escherichia coli; hipa hipa7; hipa; hipa7 ... See more keywords
Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase
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DOI: 10.1128/mbio.01138-19
Abstract: Bacterial toxin-antitoxin (TA) modules confer multidrug tolerance (persistence) that may contribute to the recalcitrance of chronic and recurrent infections. The first high-persister gene identified was hipA of Escherichia coli strain K-12, which encodes a kinase… read more here.
Keywords: hipa; kinase; gene; hipt ... See more keywords