Interval Cytoreductive Surgery and Cisplatin- or Paclitaxel-Based HIPEC for Advanced Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.17676
Abstract: Key Points Question Is paclitaxel-based hyperthermic intraperitoneal chemotherapy (HIPEC) safe and associated with equivalent outcomes as cisplatin-based HIPEC in the treatment of advanced ovarian cancer after interval cytoreductive surgery? Findings In this cohort study with… read more here.
Keywords: paclitaxel based; based hipec; advanced ovarian; ovarian cancer ... See more keywords
Hyperthermic Intraperitoneal Chemotherapy for Ovarian and Colorectal Cancer: A Review.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2021.0580
Abstract: Importance The peritoneal surface is a common site of disease in ovarian and colorectal cancer. Peritoneal metastases carry a poor prognosis, despite maximal therapeutic efforts, including surgical removal of tumor deposits and intravenous chemotherapy. Hyperthermic… read more here.
Keywords: chemotherapy; hyperthermic intraperitoneal; colorectal cancer; ovarian colorectal ... See more keywords
Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34124
Abstract: The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) with cisplatin to interval cytoreductive surgery improves recurrence‐free (RFS) and overall survival (OS) in patients with stage III ovarian cancer. Homologous recombination deficient (HRD) ovarian tumors are usually… read more here.
Keywords: effect hipec; hrd brcawt; hipec;
Reply to: Comments on “Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial”
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34219
Abstract: “ Effect of HIPEC according to HRD/ BRCA wt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial. In our study, we performed post hoc exploratory analysis of the effect… read more here.
Keywords: effect; hipec according; profile; hipec ... See more keywords
[Perioperative management for CRS and HIPEC : Anesthesiological aspects].
Sign Up to like & getrecommendations! Published in 2019 at "Der Anaesthesist"
DOI: 10.1007/s00101-019-00706-4
Abstract: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are therapeutic options for the treatment of intra-abdominal neoplasms. Following the resection of all visible tumor areas by CRS, microscopic tumor areas are treated with HIPEC. This procedure increases… read more here.
Keywords: management crs; hipec anesthesiological; crs; hipec ... See more keywords
Oxaliplatin versus mitomycin C in HIPEC for peritoneal metastasis from colorectal cancer: a systematic review and meta-analysis of comparative studies
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-020-03702-y
Abstract: Hyperthermic intraperitoneal perfusion chemotherapy (HIPEC) following cytoreductive surgery (CRS) has been applied for peritoneal metastasis (PM) from colorectal cancer (CRC). This study aimed to compare oxaliplatin (OX) with mitomycin C (MMC) in HIPEC for PM… read more here.
Keywords: metastasis colorectal; colorectal cancer; peritoneal metastasis; hipec ... See more keywords
Reply to “Is there a promising role of HIPEC in patients with advanced mucinous ovarian cancer?” by lavazzo et al
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05647-7
Abstract: We thank Dr Iavazzo et al. for their interest in our paper [1]. We agree that the outcomes of patients with advanced mucinous ovarian carcinoma (MOC) are extremely poor. Our paper underlines the pivotal role… read more here.
Keywords: pathology; advanced mucinous; role; mucinous ovarian ... See more keywords
Robotic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: is there a benefit?
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DOI: 10.1007/s00464-024-11199-7
Abstract: Open cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a therapeutic option for the management of malignancies with peritoneal carcinomatosis and of peritoneal origin. Robotic surgery shows promise as a minimally invasive approach for… read more here.
Keywords: surgery; crs hipec; cytoreductive surgery; hyperthermic intraperitoneal ... See more keywords
Oxaliplatin versus Mitomycin C following complete cytoreduction for colorectal peritoneal metastases: a comparative study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-019-04447-y
Abstract: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) can offer selected patients with colorectal peritoneal metastases (CRPM) a favorable long-term survival. While cytoreductive techniques are standardized, there remains great variability in HIPEC drugs with mitomycin… read more here.
Keywords: complete cytoreduction; colorectal peritoneal; peritoneal metastases; mitomycin ... See more keywords
Prognostic Impact and Utility of Immunoprofiling in the Selection of Patients with Colorectal Peritoneal Carcinomatosis for Cytoreductive Surgery (CRS) and Heated Intraperitoneal Chemotherapy (HIPEC)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-020-04886-y
Abstract: Background Recent studies have shown an association in non-metastatic colorectal cancer between patient survival and immunoprofiling (expression of CD3, CD4, CD8, CD45, and FOXP3 T cells at the invasive margin (IM) and the tumor center… read more here.
Keywords: carcinomatosis; crs; cytoreductive surgery; peritoneal carcinomatosis ... See more keywords
The use of cisplatin plus doxorubicin or paclitaxel in hyperthermic intraperitoneal chemotherapy (HIPEC) for stage IIIC or IV epithelial ovarian cancer: a comparative study
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-019-02065-3
Abstract: PurposeOur main aim is to analyze the survival results in women operated on for advanced ovarian cancer with two different HIPEC regimens (cisplatin plus doxorubicin versus paclitaxel).Patients and methodsA prospective cohort of patients with stage… read more here.
Keywords: group; ovarian cancer; plus doxorubicin; cancer ... See more keywords