The HIPK2/CDC14B-MeCP2 axis enhances the spindle assembly checkpoint block by promoting cyclin B translation
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DOI: 10.1126/sciadv.add6982
Abstract: Mitotic perturbations activate the spindle assembly checkpoint (SAC) that keeps cells in prometaphase with high CDK1 activity. Prolonged mitotic arrest is eventually bypassed by gradual cyclin B decline followed by slippage of cells into G1… read more here.
Keywords: mecp2; spindle assembly; assembly checkpoint; hipk2 cdc14b ... See more keywords