Age‐related effects on the anterior and posterior hippocampal volumes in 6–21 year olds: A model selection approach
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23487
Abstract: Although recent studies support significant differences in intrinsic structure, function, and connectivity along the longitudinal axis of the hippocampus, few studies have investigated the normative development of this dimension. In addition, factors known to influence… read more here.
Keywords: age related; hippocampal; posthc; age ... See more keywords
Morphological and molecular markers of mouse area CA2 along the proximodistal and dorsoventral hippocampal axes
Sign Up to like & getrecommendations! Published in 2023 at "Hippocampus"
DOI: 10.1002/hipo.23509
Abstract: Hippocampal area CA2 is a molecularly and functionally distinct region of the hippocampus that has classically been defined as the area with large pyramidal neurons lacking input from the dentate gyrus and the thorny excrescences… read more here.
Keywords: hippocampal; area; along proximodistal; molecular markers ... See more keywords
Co-injection of Aβ1-40 and ApoE4 impaired spatial memory and hippocampal long-term potentiation in rats
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.03.043
Abstract: Apolipoprotein E4 (APOE4) allele located on chromosome 19 is a major genetic risk factor for developing Alzheimer's disease (AD). However, the direct effects of ApoE4 on the cognitive function and long-term synaptic plasticity have not… read more here.
Keywords: term; spatial memory; long term; hippocampal ... See more keywords
Forskolin reverses the O-GlcNAcylation dependent decrease in GABAAR current amplitude at hippocampal synapses possibly at a neurosteroid site on GABAARs
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-66025-w
Abstract: GABAergic transmission is influenced by post-translational modifications, like phosphorylation, impacting channel conductance, allosteric modulator sensitivity, and membrane trafficking. O-GlcNAcylation is a post-translational modification involving the O-linked attachment of β-N-acetylglucosamine on serine/threonine residues. Previously we reported… read more here.
Keywords: neurosteroid site; phosphorylation; glcnacylation; hippocampal ... See more keywords
Long-duration hippocampal sharp wave ripples improve memory
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aax0758
Abstract: Longer ripples make better memories Sharp wave ripples in the hippocampus are thought to play a role in memory formation and action planning. Fernández-Ruiz et al. used multisite electrophysiological recordings combined with optogenetic activation of… read more here.
Keywords: long duration; sharp wave; duration; hippocampal ... See more keywords
Effects of propofol on the cognition and hippocampal N-methyl-D-aspartate subunits expression in an MPTP-induced Parkinson’s disease rat model
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2025.1607421
Abstract: Introduction Parkinson’s disease (PD) is associated with higher risk of cognitive impairment. Until now, little is known about the effect of anesthetics on cognitive function in PD patients. The imbalance of hippocampal N-methyl-D-aspartate (NMDA) receptors… read more here.
Keywords: nr2a nr2b; methyl; mptp induced; hippocampal ... See more keywords