Neonatal isolation modulates glucocorticoid-receptor function and synaptic plasticity of hippocampal and amygdala neurons in a rat model of single prolonged stress.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2018.12.084
Abstract: BACKGROUND Early life and stressful experiences affect hippocampal and amygdala structure and function. They also increase the incidence of mental and nervous system disorders in adults. However, prospective studies have yet to show if early-life… read more here.
Keywords: neonatal isolation; single prolonged; sps alone; stress ... See more keywords
Multimodal hippocampal and amygdala subfield volumetry in polygenic risk for Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2020.08.022
Abstract: Preclinical models of Alzheimer's disease (AD) suggest that volumetric reductions in medial temporal lobe (MTL) structures manifest before clinical onset. AD polygenic risk scores (PRSs) are further linked to reduced MTL volumes (the hippocampus/amygdala); however,… read more here.
Keywords: polygenic risk; alzheimer disease; hippocampal amygdala; mtl ... See more keywords
Hippocampal and Amygdala Gray Matter Loss in Elderly Controls with Subtle Cognitive Decline
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2017.00050
Abstract: In contrast to the idea that hippocampal and amygdala volume loss occur in late phases of neurodegeneration, recent contributions point to the relevance of preexisting structural deficits that are associated with aging and are independent… read more here.
Keywords: volume; elderly controls; hippocampal amygdala; cognitive decline ... See more keywords