Tau and amyloid-related pathologies in the entorhinal cortex have divergent effects in the hippocampal circuit
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2017.08.015
Abstract: The entorhinal cortex (EC) is affected early in Alzheimer's disease, an illness defined by a co-occurrence of tau and amyloid-related pathologies. How the co-occurrence of these pathologies in the EC affects the hippocampal circuit remains… read more here.
Keywords: entorhinal cortex; amyloid related; hippocampal circuit; tau amyloid ... See more keywords
Microglial infiltration mediates cognitive dysfunction in rat models of hypothalamic obesity via a hypothalamic-hippocampal circuit involving the lateral hypothalamic area
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.971100
Abstract: This study aimed to explore the mechanism underlying cognitive dysfunction mediated by the lateral hypothalamic area (LHA) in a hypothalamic-hippocampal circuit in rats with lesion-induced hypothalamic obesity (HO). The HO model was established by electrically… read more here.
Keywords: hippocampal circuit; cognitive dysfunction; circuit; hypothalamic hippocampal ... See more keywords