Integrative Transcriptomic Analyses of Hippocampal-Entorhinal System Subfields Identify Key Regulators in Alzheimer's Disease.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300876
Abstract: The hippocampal-entorhinal system supports cognitive function and is selectively vulnerable to Alzheimer's disease (AD). Little is known about global transcriptomic changes in the hippocampal-entorhinal subfields during AD. Herein, large-scale transcriptomic analysis is performed in five… read more here.
Keywords: pathology; hippocampal entorhinal; alzheimer disease; entorhinal system ... See more keywords
The hippocampal‐entorhinal system represents nested hierarchical relations between words during concept learning
Sign Up to like & getrecommendations! Published in 2021 at "Hippocampus"
DOI: 10.1002/hipo.23320
Abstract: A fundamental skill of an intelligent mind is that of being able to rapidly discover the structural organization underlying the relations across the objects or the events in the world. Humans, thanks to language, master… read more here.
Keywords: entorhinal cortex; hippocampal entorhinal; entorhinal system; system represents ... See more keywords
Hippocampal and entorhinal structures in subjective memory impairment: a combined MRI volumetric and DTI study
Sign Up to like & getrecommendations! Published in 2017 at "International Psychogeriatrics"
DOI: 10.1017/s1041610216002349
Abstract: ABSTRACT Background: Subjective memory impairment (SMI) is common among older adults. Increasing evidence suggests that SMI is a risk factor for future cognitive decline, as well as for mild cognitive impairment and dementia. Medial temporal… read more here.
Keywords: hippocampal entorhinal; memory impairment; study; subjective memory ... See more keywords
A Hippocampal-Entorhinal Cortex Neuronal Network for Dynamical Mechanisms of Epileptic Seizure
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Transactions on Neural Systems and Rehabilitation Engineering"
DOI: 10.1109/tnsre.2023.3265581
Abstract: Temporal lobe epilepsy (TLE) is thought to be associated with neuronal hyperexcitability in the hippocampal-entorhinal cortical (EC) circuit. Due to the complexity of the hippocampal-EC network connections, the biophysical mechanisms of the different circuits in… read more here.
Keywords: network; seizure; entorhinal cortex; cortex neuronal ... See more keywords
A map of abstract relational knowledge in the human hippocampal–entorhinal cortex
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DOI: 10.7554/elife.17086
Abstract: The hippocampal–entorhinal system encodes a map of space that guides spatial navigation. Goal-directed behaviour outside of spatial navigation similarly requires a representation of abstract forms of relational knowledge. This information relies on the same neural… read more here.
Keywords: knowledge; hippocampal entorhinal; human hippocampal; map abstract ... See more keywords